Biolayer Interferometry – Typical applications

Biolayer Interferometry – Typical applications

Kinetic applications

Protein-protein interactions
Antibody characterization
Antibody-antigen binding
Protein-small molecule interactions
DNA-aptamer binding
Bacteria-antibody interactions
Virus-like particle-antibody/protein binding
GPCR-protein binding

Quantitative applications

Antibody quantitation
ELISA replacement
Protein quantitation in crude extracts
Detection of contaminations

Screening applications

DNA-aptamer screening
Small molecule fragment screening
Secondary screening and hit validation
Inhibitor screening

Assay development applications

Formulation development
Media development

For notes and literature describing the use of the Octet® systems for the characterization of biomolecular interactions please refer to application notes provided by PALL FortéBio.